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This small molecule compound demonstrates exceptional ability to block nicotinamide N-methyltransferase enzyme activity, preventing NAD+ depletion while activating sirtuin pathways associated with healthy aging and metabolic optimization

Biochemical Characteristics 5-Amino-1MQ is a quinolinium-based small molecule compound structurally related to molecules involved in nicotinamide metabolism

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After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose