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You lose weight with Semaglutide by feeling less hungry and eating fewer calories
That suggests the system is actively adapting to defend the new body weight. These metabolic shifts may help explain why weight loss eventually plateaus despite continued drug treatmentand why weight regain can occur so rapidly once treatment stops
Accessed 20 Jun 2022 Frias JP, Bonora E, Nevarez Ruiz L et al (2021) Efficacy and safety of dulaglutide 3.0 mg and 4.5 mg versus dulaglutide 1.5 mg in metformin-treated patients with type 2 diabetes in a randomized controlled trial (AWARD-11)
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