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The typical beyond-use date is 90 days from the compounding date, which is significantly shorter than the shelf life of FDA-approved semaglutide products

9 These clinical findings are consistent with preclinical data that berberine activates AMPK and favorably alters lipid metabolism, but the trial did not directly measure GLP-1 or gut microbiota composition

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Supplement allocation was implemented using 6-digit randomization codes, with the list generated by an unblinded individual not involved in conducting the study