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The lethal concentration (LC 50 ) for HThF cells was ~ 1 M, while the LC 50 for the PTC cell lines was substantially less (0.050.5 M)
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One study found that 90% of individuals experienced adverse side effects in the first eight weeks of treatment, while another study found that 70% of diabetes patients discontinued use after 2 years due to feeling chronically sick
An important nuance: while the trials did not publish detailed BMI-stratified results in their primary papers, the data consistently shows that higher baseline BMI correlates with greater absolute weight loss in kilograms, while lower baseline BMI correlates with greater percentage weight loss
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