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In breast cancer, transcription factor AP-2 gamma (TFAP2C) is an important transcription factor that regulates estrogen receptor-alpha (ER) and c-ErbB2/HER2 (Her2), which are involved in the establishment of the gene expression pattern observed in different clinical phenotypes of breast cancer [79, 80]

29 HansenH.FabriciusK.BarkholtP.NiehoffM.MorleyJ.JelsingJ.et al (2015)

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That being said, it is perfectly possible to intake all of the amino acids needed if you are following a largely plant-based diet