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This event is thoroughly documented clinically and leads to suppression of the levels of LH, FSH, and sex steroids and inhibition of the growth of prostatic and breast cancers, as reviewed in Schally et al

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KEY POINTS Harmful Reactive Oxygen Species (ROS), including hydrogen peroxide, accumulate during cell respiration

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A 2017 meta-analysis found no significant increase in pancreatitis or pancreatic cancer risks (odds ratios 0.93 and 0.94, respectively)

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Additionally, patients in the HGSH group (high GSH intake, 16 days) exhibited an elevated recurrence rate compared to that in the LGSH group (low GSH intake, 0.05) (Supplementary Table 4)

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