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Orlistat has important drug interactions, including with ciclosporin (avoid or monitor closely if unavoidable), warfarin (monitor INR), levothyroxine (separate by at least 4 hours and monitor TSH), antiepileptics (monitor for changes in seizure frequency), and acarbose (avoid combination)

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Many advertise GLP-1-like effects or claim to mimic Ozempic. None of these products contain authentic, pharmacologically active GLP-1 analogs