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A previous study has shown that semaglutide is metabolised prior to excretion, with semaglutide-related material excreted in both urine and faeces (only 3% elimination of intact semaglutide in urine) [11]
10.1016/j.biopha.2018.10.130 183 ShohamY.KriegerY.TamirE.SilbersteinE.Bogdanov-BerezovskyA.HaikJ.et al (2018)
Ahmad N, Adhami VM, Afaq F, Feyes D, Mukhtar H
Animal and translational work hints at synergy between estrogen signaling and GLP-1 pathways, raising the possibility that fluctuating sex hormone states (menstrual cycle, menopause, exogenous hormones) may shape both efficacy and side-effect profiles (Vigil et al., 2022
2019;11:eaaw1565
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