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The FDA has also warned consumers about risks tied to unapproved GLP-1 drugs and some compounded versions, including dosing errors and concerns about products marketed with semaglutide salt forms (such as semaglutide sodium or semaglutide acetate) or products sourced from non-verified sellers
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However, the known contraindications that clinicians must observe include personal or family history of medullary thyroid carcinoma and multiple endocrine neoplasia syndrome type 2 (MEN 2), both related to thyroid C-cell concerns identified in rodent studies
Dosing Schedules and Administration Both medications follow gradual dose escalation to minimize side effects, but the schedules differ in timeline and complexity
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