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Abbreviations AF: Allele frequency CMN: Congenital melanocytic nevus CMNS: Congenital melanocytic nevus syndrome CNS: Central nervous system CpG: Cytosine (C)phosphate (p)Guanine (G) CSF: Cerebrospinal fluid DNA: Deoxyribonucleic acid MEK: MAPK/ERK kinase (MAPK = Mitogen-Activated Protein Kinase) MITF1 : Microphthalmia-Associated Transcription Factor 1 MPRAGE: Magnetization-Prepared Rapid Gradient-Echo MRI: Magnetic resonance imaging NGS: Next generation sequencing NRAS : Neuroblastoma RAS proto-oncogene PTEN : Phosphatase and tensin homolog RAF: RAF (Rapidly Accelerated Fibrosarcoma) serine/threonine kinases RAS : RAS (RAt Sarcoma) proto-oncogene TERT : Telomerase reverse transcriptase TERT-p : Telomerase reverse transcriptase promoter TSE: Turbo spin echo UV: Ultraviolet References Kinsler VA, Thomas AC, Ishida M, Bulstrode NW, Loughlin S, Hing S et al (2013) Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS

On the other hand, surgical removal of the fallopian tubes followed by assisted reproductive measures may be recommended to women with severe tubal disease affecting both tubes

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