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Because cellular iron output is mediated by FPN1 and polycupric ferrous oxide enzymes (such as ceruloplasmin), a decrease in the expression of FPN1 or ceruloplasmin can increase the sensitivity of cells to ferroptosis [29,30,31,32]

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17 BranisteV.Al-AsmakhM.KowalC.AnuarF.AbbaspourA.TothM.et al (2014)

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doi: 10.1016/j.jid.2025.03.018 37 LinWLuXYangHHuangLHuangWTangYet al

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Frequently Asked Questions The bundle is used in laboratory studies investigating growth hormone signaling, receptor interaction, endocrine pathway regulation, and cellular response mechanisms

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