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The overaccumulation of triacylglycerol and cholesterol in the hepatocytes and the overproduction of reactive oxygen species (ROS) both lead to local inflammatory responses

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Some patients report feeling uncomfortably full even after small meals, which can be accompanied by belching or the need to pass wind more frequently

Azzam EI, Jay-Gerin J-P, Pain D (2012) Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

Some patients unconsciously or deliberately increase caloric intake during non-suppressed periods or consume calorie-dense beverages that don't trigger the same satiety response as solid foods