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Physiol Behav (1983) 30(4):6636

Lyophilization, or freeze-drying, is a sophisticated process that removes water from the peptide under deep vacuum and frigid temperatures

Lets break down some possible reasons people feel different on GLP-1 meds: 1

Weighing risk versus benefit is key here, but both Levy and Salas-Whalen pointed out that untreated obesity carries risks and shouldn't be overlooked

GLP-1 medications are part of a class of treatments that mimic a naturally occurring hormone responsible for regulating hunger, blood sugar, and fullness signals