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Commentary re: J
Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
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All completely consistent with what weve seen in prior studies in type 2 diabetes, now with excellent pull-through in obesity. Together, the lipid and insulin sensitivity signals support the idea that Revitas effects may extend beyond calorie intake to deeper metabolic regulation
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