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Furthermore, imbalances in gut microbiota can impair the production of crucial metabolites like SCFAs, disrupting gut-brain signaling and leading to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis
For those who do not achieve adequate results on Wegovy or Zepbound, a drug with stronger efficacy could represent the logical next step in treatment
Retatrutide is a triple hormone (GIP, GLP-1 and glucagon) receptor agonist in development for the treatment of obesity
Diabetes Care 28:12451249 Van Cauter E, Mestrez F, Sturis J, Polonsky KS (1992) Estimation of insulin secretion rates from C-peptide levels
Semaglutide functions by mimicking the activity of an incretin hormone, which helps to regulate insulin secretion
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