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Some clinicians prefer to reduce the dose stepwise (for example, moving from a higher to lower maintenance dose before stopping completely) to allow for metabolic adjustment and medication changes

The fatty-diacid handle drives reversible albumin binding, extending the elimination half-life of the molecule to approximately 159 to 195 hours

Vitamin B 6 Vitamin B 6 is a crucial B vitamin that is involved in the production of proteins in the body, neurotransmitters that help regulate mood, red blood cell formation and the proper functioning of the immune system

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These may include: Nausea (affecting approximately 20-40% of patients, depending on the specific medication) [17] Mild abdominal discomfort or bloating Changes in bowel habits , including constipation or occasionally diarrhoea Reduced appetite , which whilst therapeutic, can feel unusual initially These effects are generally mild to moderate and tend to improve as the body adjusts to the medication, typically within 24 weeks