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Summary: Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, and glucagon) showing promising liver fat reduction in Phase 2 trials, but it does not yet hold UK marketing authorisation
The treatment benefit for heart failure with preserved ejection fraction, accounting for more than half of heart failure cases, has now been replicated
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The highest approved dose of Semaglutide (Wegovy) is 2.4 mg weekly , the target maintenance dose
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