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UA (16 mg/kg, intravenously) reduced infarct volume, improved neurological function, attenuated the inflammatory response, and improved the benefits of rt-PA (10 mg/kg) in a stroke model [146]

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The mechanism difference (tissue repair via angiogenesis vs gene expression modulation) is exactly what makes them complementary in combination formulations rather than substitutes for each other

We performed both alkaline comet assay, that detects mainly SSBs and DSBs, and neutral comet assay, that specifically detects DSBs, to discriminate the type of lesion induced by the virus