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By inhibiting NNMT, 5-Amino-1MQ may increase intracellular NAD+ levels and SAM availability, linking it to sirtuin activity, methylation capacity, and adipocyte differentiation research

Two downstream consequences are mechanistically central: nicotinamide is preserved for re-entry into the NAD+ salvage pathway (raising intracellular NAD+ availability), and SAM is preserved for other methylation reactions

Compound Reference Data Compound: 5-Amino-1MQ CAS Number: 13441-78-4 Molecular Formula: C10H11IN2 Molecular Weight: 286.11 g/mol Sequence: Synonyms: Selected Published Studies The following peer-reviewed studies were conducted using animal models or in vitro cell-culture systems

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