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Source: Novo Investor Day 2022 Estimating the costs associated with diseases are inherently imprecise and noisy due to difficulties in normalising the difference between individual circumstances and lifestyles, but for the sake of providing ball-park figures, some studies have found that excess medical spending on obesity for adults is around 260 billion USD or around 1800 USD excess per person in 2019

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Those who interrupted GLP-1 treatment and subsequently resumed before the end of the three-year trial period experienced less benefit compared to those who stayed on the medication, with longer gaps in treatment corresponding to smaller reductions in cardiovascular risk