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Figure 1 demonstrates that diminished Se levels and decreased thioredoxin reductase 1 (TXNRD1) expression compromise antioxidant defense in the thyroid gland

Beta-cells mainly accounted for the immunoreactivity, although GLP-1R expression in other rare endocrine cells cannot be fully excluded

12,25 Tirzepatide, by contrast, exerts its effects through dual agonism of both GIP and GLP-1 receptors, resulting in a distinct pharmacological profile

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