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Testing b12 after 6 to 12 months of semaglutide use makes more sense than presumptive supplementation
If you indicate you have type 2 diabetes, the projection is adjusted based on the SURMOUNT-2 and STEP-2 trial data, which showed moderately lower average weight loss in this population 3,4
For example, its not yet known whether microdosing can achieve the same level of weight loss as standard doses
Foundayo vs Wegovy: How do they compare for weight loss
The most significant clinical data for retatrutide to date comes from a Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023)
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