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Early evidence suggests substantial weight loss potential in clinical trials
Oral non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen may be considered for short-term use, but discuss with your GP or pharmacist first, particularly if you have diabetes-related kidney concerns, heart disease, or gastrointestinal risks
People with obesity or overweight who took a daily Wegovy pill 25 milligrams of oral semaglutide for a year and three months lost 13.6% of their body weight on average, compared to 2.2% for those who took a placebo
IBS patients have increased levels of mast cells, lymphocytes, and mucosal T cells, which suggests an immunological activation involvement (5, 6)
Therefore, clinical validation of the effect of adding GLP-1 to metformin treatment in improving beta cell survival and delaying disease progression is warranted
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