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Bimagrumab, a monoclonal antibody targeting activin type II receptors, has shown potential to increase lean mass while reducing fat mass
You can check the manufacturers website for more information and eligibility requirements
These two trials studied the patients who are genuinely hard to treat people with type 2 diabetes, and people with Class 2/3 obesity and established cardiovascular disease
Most common side effects were gastrointestinal, with 24.5% of participants in the phase 2 obesity trial discontinuing efinopegdutide 10 mg due to AE however when the same dose was used with gradual escalation at the MASLD trial (starting dose 2.4 mg for 4 weeks, then 5 mg for 4 weeks and then 10 mg), only 5.6% of participants discontinued the medication due to AE
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