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As a GLP-1 receptor agonist, Ozempic mimics the effects of the natural hormone by binding to GLP-1 receptors in the body

Current evidence suggests that most patients regain significant weight within one year of stopping semaglutide, indicating that this is likely a long-term or indefinite therapy for obesity management rather than a short-term intervention

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Reactions were run using the DNA Engine Opticon 2 Continuous Fluorescence Detector System (Applied Biosystem, Grand Island, NY)

The extent of direct blood-brain barrier penetration varies by agent