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Mice from a different substrain and vendor, but fed similar lean and high-fat diets to this study, showed a predominance of the family Erysipelotrichaceae, of which Ileibacterium is a genus, in their cecal microbiomes 76

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In other words, the drug itself may not directly damage the retina

FDA Approval Details The FDA granted approval based on results from the OASIS clinical trial programme and the SELECT cardiovascular outcomes trial

Shamsi FA, Chaudhry IA, Boulton ME, Al-Rajhi AA