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Discontinuation of therapy due to clinical adverse reactions was similar to the placebo treatment group (sitagliptin and metformin, 1.9%
Participants in the STEP 1 trial lost an average of 10-15% of their body weight after 68 weeks, with most of the reduction occurring in the first year
Life gets busy, and missing a dose happens to almost everyone at some point
"Shifts in your diet, including fewer fatty acids and less water, can contribute to dryness of your skin," she explains
The AngioSafe 1 study, which is also designed to clarify the association between exposure to GLP-1R agonists and diabetic retinopathy through clinical and preclinical study designs found no risk for severe diabetic retinopathy when patients were treated with GLP-1R agonists, and no effect of GLP-1R agonists on angiogenesis (Gaborit et al., 2020)
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