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To address the extremely short half-life (2 min) of native human GLP-1, structural modifications have been applied to GLP-1 RAs and a dual GLP-1/GIP RA
These risk differences might be explained by additional mechanisms beyond the actions of GLP-1 RAs on vasculature, including the chronotropic effects of GLP-1 RAs which may blunt cardiac protection ( Unstable angina pectoris: An umbrella review of meta-analyses of RCTs including 56,004 patients with diabetes, prediabetes, and at high risk of diabetes, found no association between GLP-1 RAs and the risk of uAP (RR = 1.06, 95%CI = 0.931.21) when compared to placebo (Zhu et al., 2020)
Shes authored a variety of books, including When I Go Low (for kids), Pregnancy with Type 1 Diabetes, and Dealing with Diabetes Burnout. Gingers also written for Diabetes Mine, Healthline, T1D Exchange, Diabetes Strong and more
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