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Every efficacy study (obesity, liver, muscle) used subcutaneous dosing, so injection is the route with the animal evidence behind it
Most people do not experience symptoms from high B12 itself
Yet, there remained always something peculiar about jamming a sharp object into someones flesh and injecting a foreign substance into them, let alone the thought of stabbing myself with one of those damn things
Drug Interactions: The clinical trials did not specifically evaluate interactions between AOD-9604 and other medications
Boyer TD (1989)
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