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This contributes to the absorption mechanism of oral vitamin B12, which does not depend only on intrinsic factors, but the absorption can be done through passive diffusion
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216 In addition, PRMT4-catalyzed asymmetric dimethylarginine (ADMA) has been reported to bind to NOS as a ligand, leading to NOS dysfunction, resulting in decreased cerebral blood flow and aggravating AD, which can be reversed by inhibition of PRMT4
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