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When used with insulin or sulfonylureas, dose adjustments of these medications may be needed to reduce hypoglycemia risk

Yuen BH et al

Gln deficiency completely eliminated the proliferation of human CD4 + T cells, and inhibition of GLS reduced the proliferation index of human CD4 + T cells during the process of CD3/CD28 signaling activation (46)

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SURMOUNT-1: What the Efficacy Data Actually Show SURMOUNT-1 is the foundational phase 3 trial for tirzepatide in weight management