Vegetarians and vegans : B12 is found predominantly in animal products, so individuals following plant-based diets may be at risk of deficiency
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Glutamate participates in diverse physiological processes, such as developmental plasticity and long-term potentiation as well as brain diseases: epilepsy, stroke, amyotrophic lateral sclerosis, Alzheimers disease, Parkinsons disease and schizophrenia (3)
Some genetic changes, like in the MTHFR gene, can affect how Vitamin B12 is used in the body
Wang X, Liu B, Xu Q, Sun H, Shi M, Wang D, Guo M, Yu J, Zhao C, Feng B