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Within gene regulatory regions, the acetylation of lysine residues of histone tails has been correlated with activation of transcription

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For example, in a randomized, double-blind, placebo-controlled trial in 60 participants diagnosed with an acute MI, neither mortality nor echocardiographic measures of cardiac function differed between patients treated with intravenous L-carnitine (6 g/day) for seven days followed by oral L-carnitine (3 g/day) for three months and those given a placebo (49)

pp 485497 Avissar S, Schreiber G, Danon A, Belmarker RH