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GLP-1 medications are considered safe for most patients with Hashimotos or hypothyroidism, as long as there is no history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, which are contraindications due to a potential cancer risk observed in animal studies

For others, the benefits may be strong enough to weigh against the side effects, especially when those side effects can be managed with guidance from a health care provider