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Before using Zepbound, it is important to tell your healthcare provider about any medical conditions you have, and if you are pregnant, planning to become pregnant, or breastfeeding
In the STEP-4 randomized trial (Rubino and colleagues, JAMA, 2021), the 803 adults who switched to placebo at week 20 regained about 6.9 percent of body weight over the next 48 weeks, while those who continued semaglutide kept losing
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