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Synthetic hormones such as birth control pills or cortisone-containing steroids (e.g., a Medrol dose-pack) can trigger the growth of excess candida (yeast), which also often damages the gut lining, with or without the existence of SIFO (small intestinal fungal overgrowth)
The FDA announced that Zepbound should be taken along with a low-calorie diet and an extensive exercise routine
Kidney problems: Signs may include swelling in the legs or feet, unusual fatigue, shortness of breath, or changes in urination, especially if dehydration occurs from vomiting or diarrhea
As far as the other polymorphic genes are concerned (NRF2, HO-1, CAT, SOD), the examined studies do not allow to confirm for each a conclusive and causative role in vitiligo onset and progression