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Animal As a senolytic, FOXO4-DRI carries mechanism-specific theoretical risks discussed in the senescence literature including disruption of beneficial senescence surveillance and off-target effects on stem-cell populations that share features with senescent cells and senolytic translation from mouse to human has a history of failures
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Variations in potency between compounding pharmacies, and even between batches from the same pharmacy, can create the impression that the medication is wearing off faster than it should
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