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These results indicate that D-galactose successfully induced an aging model in mice
The involvement of medicinal chemists will also help delineate the impacts of different structural changes, such as different terminal linkages with GSH ( C -terminal, S -terminal, and N -terminal), on binding selectivity and efficiency, and establish structure-activity relationships (SAR) for the development of glutathione transporter-based brain targeting ligands
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Mocchegiani 2012
Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JS (2011)
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