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ClinicalTrials.gov is the authoritative place to check if that ever changes

Participants also reported visible improvements in skin tone and texture, with no irritation or adverse effects

Although these drugs may slow the rate of cognitive decline by lowering blood glucose and enhancing central insulin signalling in the brain, patients can experience adverse effects such as decreased appetite, nausea, abdominal discomfort and diarrhoea while taking them (11)

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