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Another core advantage of a TTE endpoint is that it is easier to interpret than a mean change from baseline comparison, given that its meaningfulness to patients is directly linked to the meaningfulness of the event, with inherent patient-centricity and interpretability

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An assortment of epidemiological and clinical studies have stated glucose and lipid metabolism alterations, insulin resistance, and central obesity as predominant factors for the development of MetS [38, 212]

Choosing the right site is key for effective absorption and to reduce the risk of adverse reactions

Dietary habits play a role, too