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A major limitation of many studies investigating the effect of KD on the skin is the lack of randomization, which significantly reduces their scientific value

In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses

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Also known as Epitalon or Epithalamin (CAS 307297-39-8), this compound has the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol