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Which Is Safer: Clinical Evidence and Individual Considerations From a pure safety standpoint, semaglutide and tirzepatide are considered comparably safe when used as directed
Current evidence suggests they are mostly neutral
Nausea is pretty common when you first start
In a 2-year study, Wegovy was associated with improvements in blood pressure, cholesterol, and A1c
Avoid these areas and consult a healthcare provider if they persist or grow
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