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10.1038/nrrheum.2012.224 Summary Keywords glucagon-like peptide-1 receptor agonists, knee osteoarthritis, obesity, treatment pathway, weight loss Citation Wu J, Lei Y, Sa R, Zhong Y and Lu Y (2026) GLP-1 receptor agonists in obesity-related knee osteoarthritis: from weight loss to therapeutic pathway reconstruction

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That means we can top off the tank but we cant overfill it