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The Phase 2 cohort lost 8.7% at 48 weeks
Functional heterogeneity of marginal zone B cells revealed by their ability to generate both early antibody-forming cells and germinal centers with hypermutation and memory in response to a T-dependent antigen
The compound lacks the androgenic properties necessary for significant protein synthesis and cellular hypertrophy
These proteins form what is called an apoptotic blockade, meaning that cells cannot undergo apoptosis, even when they experience DNA damage that would normally trigger cell death
The constant exposure of the renal system to toxins can cause nephrotoxicity (toxicity in the kidneys) which affects renal function
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