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ChaC2 is a constitutively expressed protein whose expression is not affected by the external environment for the basal turnover of GSH [37]

Liubas et al

Recent technological advances have expanded beyond transcriptomics to include single-cell proteomics through technologies such as CyTOF (Cytometry by Time-Of-Flight) and targeted antibody panels, enabling simultaneous measurement of dozens of proteins in individual cells [7, 26]

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Conjugation proceeds as a nucleophilic displacement reaction with the glutathione anion (GS - ) serving as the nucleophile