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We used NMR spectroscopy to identify the crucial region within the p53 TAD responsible for FOXO4 binding (Figure

After incubation for 12h, the cells were washed with PBS (pH 7.4) and stained with DCFH-DA or DHE at 37 C for 20 min

Closer immunophenotyping of the cellular content of the BALF and lung tissue by flow cytometry showed that AA-exposed mice had significantly greater levels of eosinophilia in both compartments compared to PBS and melatonin-only controls ( Figures 1G, H )

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Modulation of antioxidant enzymes, SIRT1 and NF-B by resveratrol and nicotinamide in alcohol-aflatoxin B1-induced hepatocellular carcinoma