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However, the clinical advancement of oridonin faced limitations [24, 25], stemming not only from its unclear molecular mechanisms but also due to hydrophobicity and deficient targeting capabilities [26,27,28,29]
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Sulforaphane activates the NRF2 pathway in the liver
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Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, and Ronai Z
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