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I can tell you an example of a patient I saw yesterday that had lost significant weight and they were taking other medications And the dose had to be adjusted significantly because of their weight loss and they didnt know that. Patients on insulin, for instance, might need a lower dose as they shed pounds while using semaglutide
They discovered that semaglutide treatment improved body composition by reducing excess body fat, notably abdominal fat, and increasing the proportion of lean body mass, or weight that is not body fat
Factors such as individual metabolism, commitment to lifestyle adjustments, and overall health status play a critical role in determining how effective either medication will be for a particular person
In: Current drug metabolism 12 (7), S
It cites STEP 1, STEP 2 and STEP 3 for semaglutide and SURMOUNT 1-4 for tirzepatide as enrolling people across varying activity levels, with average weight loss of 5-10% without structured fitness
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