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A large-scale analysis of Reddit, TikTok, and YouTube posts specifically identified sleep and insomnia as one of the key concerns users reported when discussing their experiences with these medications
Eat half first and keep the rest for later if early fullness hits
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The anchoring trials are STEP (semaglutide for weight management, NEJM 2021), SURMOUNT (tirzepatide for weight management, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)
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