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Systematic review on daily vitamin B12 losses and bioavailability for deriving recommendations on vitamin B12 intake with the factorial approach

Still, any time you put a needle in your arm or glute (common injection sites), theres a risk of some swelling at the site

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Medical Conditions: Tell your provider if you have Leber's hereditary optic neuropathy, polycythemia vera, or gout, as B12 injections may affect these conditions

The other consistent context in the preclinical literature is a metabolic environment the mouse studies pair the compound with diet/energy-balance conditions rather than testing it in isolation